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Mesothelioma - what causes mesothelioma besides asbestos Causes Mesothelioma?

Like all cancers, mesothelioma can be difficult to recognize because its symptoms can resemble other diseases. Early diagnosis and treatment can help improve the prognosis of a patient.

Asbestos exposure is the main cause of mesothelioma. Asbestos is a group minerals that can be separated into long, thin fibres. When inhaled or consumed asbestos fibers can become stuck in the lining of certain organs.

Exposure to Asbestos

The most well-known reason for mesothelioma is exposure to asbestos. Asbestos is a naturally occurring mineral that is composed of microscopic, strong fibers. It was widely used in automobiles, buildings, and a myriad of construction materials from the 1930s to the early 1980s due to the fact that it was resistant to water, fire and sound. Makers of asbestos-based products knew about the dangers to health however they did not inform the public.

The greatest exposure risk was for those who directly handled asbestos-containing products. Mining, asbestos removal, shipbuilding and other industrial jobs exposed workers to huge amounts of asbestos. Asbestos-containing materials, such as shingles, pipes and glues and talcum powder were used in the home by people who were also exposed. Chrysotile asbestos is the most popular kind of asbestos that is used in the United States. However, other kinds of asbestos, like amosite and crocidolite, also have been linked to mesothelioma.

The signs of mesothelioma generally don't show up until decades after asbestos exposure. Once symptoms appear, the disease can quickly progress and be fatal. Symptoms most often affect the lungs (pleural mesothelioma) but they can also affect the lining of the stomach and testicles, or in the heart.

When asbestos fibres are inhaled or swallowed they adhere to cells that connect the body's organs and tissues. This causes genetic mutations which result in cancer. The cancerous cells expand uncontrollably, and eventually form tumors.

People who work in industries that are exposed to asbestos more often are at a greater risk of developing mesothelioma. The most at risk are men who had blue-collar jobs or served in the military. However, mesothelioma can develop in women who were exposed to asbestos, particularly in the case of family members exposed to asbestos while at work.

Secondary exposure can occur when someone who is at risk of developing mesothelioma brings asbestos fibres home on their clothes and clothes. This has happened to spouses of asbestos-exposed people, as well as some tile and hairdressers. Some studies have revealed that a mineral called erionite, which is similar to asbestos, increases the chance of developing pericardial mesothelioma cause. However it has not been confirmed by other studies.

Exposure to minerals

The cells that line the chest (pleura), abdominal cavity, as well as other body parts undergo a change. Mesothelioma may also develop in the linings of the heart (pericardium) or testicles. The disease is most commonly caused by exposure to asbestos, however there are other causes.

Asbestos is a naturally occurring mineral, is made up of microscopic and strong fibers. It was used for building material, in brakes for automobiles as well as for a variety of other products from the 1930s to the 1980s because it was resistant to water, fire, and sound. A lot of people working employed in the construction industry or military were exposed. Workers who removed and handled asbestos were especially at risk of breathing asbestos-containing particles.

Although the exact mesothelioma risk differs by job, any asbestos exposure increases the likelihood of developing the disease. Mesothelioma has been linked to all kinds of occupations and industries, but most often, it is seen in miners, millers shipyard workers and asbestos producers. It has also been found in workers involved in the manufacturing of automobiles and aircraft as well as those who handled or processed insulation.

Mesothelioma typically develops slowly, but symptoms can occur between 20 and 60 years after asbestos exposure. It's important that everyone consult a doctor about mesothelioma, even if they haven't had any experience with asbestos in the past. The earlier the cancer is identified the easier it is to treat it successfully.

In the past, many who were diagnosed with mesothelioma failed to get diagnosed until their illness had advanced. Since mesothelioma cancer is extremely rare doctors tend to overlook signs such as persistent coughing or breathing difficulties.

Asbestos was eliminated by the 1980s. However those who worked in the military or in the industrial sector prior to the time were still at a higher risk of mesothelioma. Researchers have recently discovered different types of mineral exposure which increase mesothelioma risks. In Turkey for instance, a mineral called erionite can be found in the soil and used to create materials. Studies on the local population who are exposed to a lot of erionite have discovered that men living in these communities are more likely to develop mesothelioma than women. Similar findings have been found with another mineral called fluoro-edenite, which is found in Italy.

Genetics

Mesothelioma can be described as a cancer that affects mesothelium. It is most prevalent in the chest cavity's lining (pleura) however it can also affect the tissue around the abdomen, heart and the testicles.

Doctors have linked mesothelioma to a mutation in the gene known as BAP1. This gene regulates a process which puts calcium in cells, and when it's mutated the person is more likely to develop cancerous cells. Scientists found that BAP1 mutants are found in 70% of mesothelioma patients. This discovery has made mesothelioma easier to detect and has increased screening, especially for those with an ancestral history.

Researchers have also discovered other genetic variants that could result in the development of mesothelioma. These mutations also helped mesothelioma experts understand the disease, and manage it.

While genetics be a factor in pericardial mesothelioma causes, asbestos remains the leading risk factor for cancer. Some people exposed to asbestos do not develop cancer, while others who are not genetically predisposed develop mesothelioma after an extended period of in exposure. Secondary exposure, or paraoccupational exposure, may occur when asbestos-exposed coworkers bring home asbestos fibers on their clothing and skin.

In some instances mesothelioma can be found in families due to the combination of genetics and asbestos exposure. The majority of mesothelioma is an unrelated illness and doesn't appear to have an ancestral history.

Asbestos-related mesothelioma can be a serious and complicated illness, but research continues to make incredible improvements in treatment and recovery options for patients. Asbestos is now banned in a number of countries around the world and scientists are constantly improving mesothelioma treatments with better drugs, more specific surgeries, how does asbestos cause mesothelioma and more efficient diagnostic tests. Download a free copy our Mesothelioma Guide to learn about how much asbestos can cause mesothelioma these recent advancements could be beneficial to you. This comprehensive resource contains an exhaustive listing of mesothelioma treatment options and includes the most recent clinical trials and promising options. Download the guide by filling in our online form or by calling directly.

Enjoy the Lifestyle

Mesothelioma is a type of cancer that affects the cells that line specific areas of the body, such as the abdomen or lungs. The majority of mesothelioma cases begin in the lining of the chest cavity (the pleura) however, it may also occur in the abdomen's lining (the peritoneum) and around the heart (the pericardium).

While asbestos exposure is the primary risk factor, other factors such as gender and age can also increase the chance of developing mesothelioma. Some of these factors, like smoking or a person's gender can be altered, whereas others, like age or family history, cannot.

Most mesothelioma patients are related to someone who has the disease and who has been exposed to asbestos for a long time. The majority of patients diagnosed with peritoneal or pleural cancer are older than 45. This is due to the fact that mesothelioma can take years to develop, and the symptoms may begin to manifest as an older patient.

A biopsy is one of the tests used by doctors to determine if pleural mesothelioma is present. Other tests include a CT scan, FDG-positron emission tomography, and a CT scan. A biopsy is the removal of a small portion of tissue to be examined under a microscope. It can be done using VATS or a type of keyhole surgery or a CT scan-guided needle.

Doctors can also test a patient's blood for a genetic mutation called BAP1. This mutation is in a gene that blocks the growth of tumors, and makes people more susceptible to malignancies caused from environmental contaminants. This mutation increases the chance of developing mesothelioma, even in the case of relatively low levels of asbestos exposure. It also reduces the duration of latency for people with this mutation. Researchers do not yet know how does asbestos cause mesothelioma (source for this article) widespread this mutation is in the general population or whether it can be cured by lifestyle choices such as avoiding exposure to toxic substances. This is an area of ongoing research.